Mr Liang Chao, PhD student of the School of Chinese Medicine was recently presented the Webster Jee Young Investigator Award at the International Chinese Musculoskeletal Research Society – Orthopaedic Research Society membership meeting held in Las Vegas for his outstanding research on bone and joint diseases.
The award-winning paper, entitled “Aptamer-functionalised delivery system for osteogenic siRNAs to achieve osteoblast-specific RNA interference for bone anabolic therapy”, introduced an aptamer-functionalised lipid nanoparticles (LNPs) delivery system to achieve accumulation of osteogenic siRNAs in osteoblasts which promotes bone formation in animal models with established osteoporosis. This study is expected to contribute to a better understanding of cellular level delivery of osteogenic siRNAs and clinical translation of RNA interference strategy in skeletal metabolic disease with impaired bone formation.
The Webster Jee Young Investigator Award is presented to awardees at the meetings of American Society for Bone and Mineral Research, Orthopaedic Research Society or the International Conference on Osteoporosis and Bone Research with the aim of recognising the achievement of young outstanding researchers.
Mr Liang Chao presents his award-winning paper at the International Chinese Musculoskeletal Research Society – Orthopaedic Research Society membership meeting