唐俊杰博士

唐俊杰博士目前在中医药学院担任研究助理教授。他在2010年於香港科技大学获得生物学学士学位，并於香港大学医学院在2013年和2017年分别取得硕士学位及博士学位。2017年至2019年，唐博士在香港浸会大学中医药学院接受博士後培训。

唐博士的研究兴趣集中在：

1. 钙信号通道在神经退行性疾病的病理生理学
2. 开发高通量筛选平台，筛选用於纠正神经退行性疾病的钙离子通道的药物单体及其衍生物
3. 开发通过纠正钙稳态失衡以治疗神经退行性疾病的治疗方法

1. Zhu Z, Yang CB, Iyaswamy A, Krishnamoorthi S, Sreenivasmurthy SG, Liu J, Wang ZY, Tong BCK, Song JX, Lu JH, Cheung KH and Li M (2019) “Balancing mTOR Signaling and Autophagy in the Treatment of Parkinson’s Disease”. International Journal of Molecular Sciences 20, 728.

2. Tong BCK*, Wu JX*, Li M and Cheung KH (2018) “Calcium Signaling in Alzheimer's Disease & Therapies”. Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1865, 1745-1760. (*Co-first authors)

3. Yang L, Gu WW, Cheung KH, Yan L, Tong BCK, Jiang YY and Yang J (2018) “InsP3R-SEC5 Interaction on Phagosomes Modulates Innate Immunity to Candida Albicans by Promoting Cytosolic Ca²⁺ Elevation and TBK1 Activity” BioMed Central Biology 2018, 16: 46

4. Tong BCK, Lee SKC, Cheng WH, Lai KO, Foskett JK and Cheung KH (2016) “Familial Alzheimer’s Disease-associated Presenilin 1 Mutants Promote g-secretase Cleavage of STIM1 to Impair Store-operated Ca²⁺ Entry”. Science Signaling 9, ra89.

5. Lee SKC, Tong BCK, Cheng WH and Cheung KH (2016) “Characterization of Two-Pore Channel 2 by Nuclear Membrane Electrophysiology”. Scientific Reports 6, 20282.

6. Hao Y, Chow AW, Yip WC, Li CH, Wan TF, Tong BCK, Cheung KH, Chan WY, Chen YC, Cheng CH and Ko WH (2016) “G Protein-coupled Estrogen Receptor Inhibits the P2Y Receptor-mediated Ca²⁺ Signaling Pathway in Human Airway Epithelia”. Pflügers Archiv-European Journal of Physiology 2016: 1-15.