Academic Seminar: Breakthrough in In situ Neural Regeneration Technology by Professor Chen Gong of Jinan University

18 September 2025

On 11 September 2025, Professor Chen Gong, Director of the Brain Repair Center at Jinan University delivered an insightful seminar titled “In situ Neural Regeneration Technology and Clinical Translation” at the School of Chinese Medicine. Hosted by Professor Li Min, Dean of Chinese Medicine, the event drew a group of distinguished audience, including Professor Bian Zhaoxiang, Associate Vice-President (Clinical Chinese Medicine); Professor Zhong Bu, Dean of School of Communication; Professor Charles Feng, Associate Dean of School of Communication, as well as research staff specialising in brain and neurological science.

Professor Chen introduced neuroregenerative gene therapy for the treatment of neurodegenerative disorders and neural injuries. He exemplified the neural transcription factor NeuroD1 to directly reprogram endogenous glial cells into functional neurons, thereby reconstructing neural circuits and restoring neurological functions. Notably, Professor Chen’s research team made a groundbreaking achievement in developing an AAV-based gene therapy for in situ neuroregeneration, culminating the world’s first gene therapy treatment for a glioblastoma patient using this approach in 2024. This milestone marks a significant step forward in translating fundamental research into clinical practice.

The seminar concluded in a lively atmosphere, with students and staff actively engaging in discussion with Professor Chen. Participants expressed that they had gained valuable insights and a deeper understanding of the prospects of in situ neural regeneration technology. This successful event not only has fostered transdisciplinary collaboration but also contributed to a positive and vibrant research environment at the School.

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(From left to right): Professor Zhong Bu, Professor Chen Gong and Professor Li Min

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Professor Chen Gong shared his innovative research on in situ neural regeneration technology with staff and students of HKBU.